Abstract: Fuchs uveitis syndrome is a chronic non granulomatous iridocyclitis characterized by posterior corneal opacities  and iris discoloration. Due to the mild inflammatory response in the early stage, it is easy to be ignored, while in the later stage, it can cause serious complications that impair vision, such as cataracts and glaucoma. Therefore, the treatment of Fuchsuveitis syndrome is mainly aimed at the treatment of complications, such as phacoemulsification combined with intraocular lens implantation, trabeculectomy or glaucoma drainage valve surgery, and the use of anti-glaucoma drugs. At present, the etiology of Fuchs uveitis syndrome is not yet clear. Some authors believe that Fuchs uveitis syndrome is a group of diseases with similar clinical manifestations caused by multiple causes, while the others believe that the disease is caused by viral infection and does not belong to the syndrome. In addition, genetics, immunity, and sympathetic nerves may also be related to Fuchs uveitis syndrome. (Int Rev Ophthalmol, 2023, 47: 264-268)

Key words: Fuchs uveitis syndrome, etiology, pathogenesis